Chancepercent27s hset - Nov 11, 2013 · An In Silico Model for HSET Binding Informs Compound Design and Synthesis of the Allosteric HSET Inhibitor CW069. Amino acid sequence alignments for the motor domains of HSET (Protein Data Bank [PDB] 2REP) and the closely related kinesin, KSP (PDB 2FKY and 3ZCW), revealed an 80% sequence similarity between the proteins in the motor domains (HSET residues 310–661).

 
Redis HSET command is used to set field in the hash stored at the key to value. If the key does not exist, a new key holding a hash is created. If the field already exists in the hash, it is overwritten. Return Value. Integer reply . Style css

Kinesin-14 family proteins are minus-end directed motors that cross-link microtubules and play key roles during spindle assembly. We showed previously that the Xenopus Kinesin-14 XCTK2 is regulated by Ran via the association of a bipartite NLS in the tail of XCTK2 with importin α/β, which regulates its ability to cross-link microtubules during spindle formation. Here we show that mutation of ...In order to investigate the effect of CW069-induced HSET inhibition on mitotic spindle morphology, as previously described for HSET depletion by siRNA (Kwon et al., 2008), we first confirmed the mitotic index, centrosome numbers, and extent of mitotic multipolarity in exponentially growing cultures of untreated N1E-115 and normal human dermal ...Sep 7, 2023 · HSET will be REMOTE on Friday, June 9, 2023 - Head to Google Classroom. Book a Virtual Teacher Tuesday meeting. Preparing for the brightest future, High School for Energy and Technology is pioneering the field of education through our dedication and commitment to our students’ needs. Here, we report the discovery of a novel 2-(3-benzamidopropanamido)thiazole-5-carboxylate with micromolar in vitro inhibition of HSET (KIFC1) through high-throughput screening and its progression to ATP-competitive compounds with nanomolar biochemical potency and high selectivity against the opposing mitotic kinesin Eg5.HSET Day started out as Health Sciences and Nursing Day, but it evolved when GCU decided to emphasize science, technology, engineering and math. Several health sciences, engineering and technology clubs set up information tables for HSET Day, including athletic training (pictured).Feb 1, 2022 · The documentation for HSET says that it returns the integer number of fields that were added. If you are modifying a field rather than adding a field, it will return 0. If you are modifying a field rather than adding a field, it will return 0. Sep 5, 2022 · HashSet: HashMap: Implements java.util.Set interface: Implements java.util.Map: Allows a single null value: Allows a single null key and any number of null values When you pass the HiSET, you receive what's known as a high school equivalency credential (HSE), which essentially stands in for a high school diploma. In order to receive an HSE credential, you have to pass five subject sections of the HiSET, called subtests. These five subtests test you on language arts reading, language arts writing, math ... 2023 Fantasy Football Cheat Sheet | Positional Rankings | FantasyPros. Week 1. Dynasty. Research. Projected Leaders. Prop Bet Cheat Sheet. Prop Bet Analyzer. Game Picks. Inactives List.HSETNX key field value. Available since: 2.0.0. Time complexity: O (1) ACL categories: @write, @hash, @fast. Sets field in the hash stored at key to value, only if field does not yet exist. If key does not exist, a new key holding a hash is created. This suggests that only a subset of the IFT machinery, including IFT52 and IFT88, interacts with HSET to promote centrosome clustering. Figure 3. IFT 88/70/52/46 complex directly interacts with HSET, and depletion of IFT88 reduces HSET turnover on mitotic spindle microtubules. Schematic representing the core of IFT‐B subcomplex.Kinesin-14/HSET, a minus end-directed motor, plays a crucial role in centrosome clustering. Accordingly, HSET is deemed to be a promising chemotherapeutic target to selectively kill cancer cells. Recently, three HSET inhibitors (AZ82, CW069 and SR31527) have been reported, but their specificity and efficacy have not been evaluated rigorously.Aster and bundle formation by HSET is context-dependent. To determine if HSET, like its Xenopus homolog XCTK2, could form MT asters, we expressed and purified four HSET truncations tagged with an ...Redis hash 命令. 查看哈希表 key 中,指定的字段是否存在。. 获取存储在哈希表中指定字段的值。. 为哈希表 key 中的指定字段的整数值加上增量 increment 。. 为哈希表 key 中的指定字段的浮点数值加上增量 increment 。. 同时将多个 field-value (域-值)对设置到哈希表 key 中 ...Jun 4, 2020 · Abstract. Centrosome amplification is a hallmark of cancer, and centrosome clustering is essential for cancer cell survival. The mitotic kinesin HSET is an essential contributor to this process. Recent studies have highlighted novel functions for intraflagellar transport (IFT) proteins in regulating motors and mitotic processes. HSET will be REMOTE on Friday, June 9, 2023 - Head to Google Classroom. Book a Virtual Teacher Tuesday meeting. Preparing for the brightest future, High School for Energy and Technology is pioneering the field of education through our dedication and commitment to our students’ needs.HSET utility or equivalent vendor-supplied software do. An alternative is to have the embedded host support a test fixture that initiates the test modes. Upon enumeration by the host, the test fixture presents a VID/PID pair that defines a test mode or operation to execute. The hset command is used to add the key-value pair to the hash, if hash does not exist then it will create new hash. The hget command is used to retrieve the value from the key which was specified. We are also using hkeys for retrieving the key which was present into the hash. Below example shows add and remove elements by using hget as follows.Best Java code snippets using redis.clients.jedis. Jedis.hset (Showing top 20 results out of 846) redis.clients.jedis Jedis hset.9U. National. | Regional. Class of 2027 HS High Follow Prospects Ranking Last Updated: 5/25/2023. Rankings Menu for 2027 Class. National High Follow Prospects By Grad Year. select. Clear filters. *Rankings for 2024 Grad and younger are available to Crosschecker Rankings & Scouting Reports and Scout subscribers.*.2023 Fantasy Football Cheat Sheet | Positional Rankings | FantasyPros. Week 1. Dynasty. Research. Projected Leaders. Prop Bet Cheat Sheet. Prop Bet Analyzer. Game Picks. Inactives List.in node.js, if you already have the key / value in an object, you can do this. await redis.hset ('myhashset', { field1: value1, field2: value2 }) i figure out that my problem was with my redis client. my redise version is 5 but my redis client doesn't support new features in Redis 5. so i use ioredis and this redis client support hmset now ...Feb 15, 2023 · Redis hdel key is defined as the key from which we are removing the field. We are creating the key by using the hset command and deleting the field by using the hdel command. In the below example, we are creating the key name as hdel_key and defining the field name as field1, field2, and field3. Jul 9, 2018 · Here, we study aster formation by human minus-end-directed kinesin-14 (HSET/KIFC1). We show that HSET is incapable of forming asters from preformed, nongrowing MTs, but rapidly forms MT asters in the presence of soluble (non-MT) tubulin. HSET binds soluble (non-MT) tubulin via its N-terminal tail domain to form heterogeneous HSET-tubulin ... Feb 4, 2021 · The documentation for Redis HSET states: 'As of Redis 4.0.0, HSET is variadic and allows for multiple field/value pairs.' Your solution is not the same as doing HMSET. Because that would only save a single string. I want to store the whole object in the database. Here, we report the discovery of a novel 2-(3-benzamidopropanamido)thiazole-5-carboxylate with micromolar in vitro inhibition of HSET (KIFC1) through high-throughput screening and its progression to ATP-competitive compounds with nanomolar biochemical potency and high selectivity against the opposing mitotic kinesin Eg5.5. The only difference between the commands HSET and HMSET is the return value of the commands. HSET return value (Integer reply): # if the field is a new field in the hash and value was set. (where # is the number of new fields created ) 0 if the field already exists in the hash and the value was updated. HMSET returns a simple string as a reply.HSET mykey field 10.50 HINCRBYFLOAT mykey field 0.1 HINCRBYFLOAT mykey field -5 HSET mykey field 5.0e3 HINCRBYFLOAT mykey field 2.0e2 Implementation details The command is always propagated in the replication link and the Append Only File as a HSET operation, so that differences in the underlying floating point math implementation will not be ...HSETNX key field value. Available since: 2.0.0. Time complexity: O (1) ACL categories: @write, @hash, @fast. Sets field in the hash stored at key to value, only if field does not yet exist. If key does not exist, a new key holding a hash is created.To assess whether the HSET/IFT protein interaction could affect the motor behavior, we then performed fluorescence recovery after photobleaching (FRAP) experiments. To monitor GFP-HSET turnover on mitotic spindle microtubules upon IFT88 depletion, GFP-HSET was introduced in an isogenic manner in the DLD-1 IFT88-AID cell line, described in Fig 1.Teams. Q&A for work. Connect and share knowledge within a single location that is structured and easy to search. Learn more about TeamsWhile working with Redis, I am running into an issue that the documentation doesn't really help much with. I am attempting to store scores as a hash within a stored value (so like a hash within group:id:ranking), which I thought would be written using hset or hmset and read using hget.Aster and bundle formation by HSET is context-dependent. To determine if HSET, like its Xenopus homolog XCTK2, could form MT asters, we expressed and purified four HSET truncations tagged with an ...May 23, 2019 · An HSET is like so: HSET myhash field1 "Hello" is there a way to put an expiration/TTL on the "field1" key. It's trivial to put an expiration on myhash tmk, but I don't know how to put a TTL on k... Php Redis: Redis hash usage example - OneLinerHub HSET has a role in controlling spindle length by cross-linking and sliding microtubules. High KIFC1 expression is associated with metastatic spread to the brain in primary non-small cell lung cancer. An analysis was made of the weak interactions of ADP-Unc104 and ADP-kinesin with microtubules and their inhibition by MAP2. RedisClient. Best JavaScript code snippets using redis. RedisClient.hset (Showing top 12 results out of 315) redis ( npm) RedisClient hset.An HSET is like so: HSET myhash field1 "Hello" is there a way to put an expiration/TTL on the "field1" key. It's trivial to put an expiration on myhash tmk, but I don't know how to put a TTL on k...HSETNX key field value. Available since: 2.0.0. Time complexity: O (1) ACL categories: @write, @hash, @fast. Sets field in the hash stored at key to value, only if field does not yet exist. If key does not exist, a new key holding a hash is created. To assess whether the HSET/IFT protein interaction could affect the motor behavior, we then performed fluorescence recovery after photobleaching (FRAP) experiments. To monitor GFP-HSET turnover on mitotic spindle microtubules upon IFT88 depletion, GFP-HSET was introduced in an isogenic manner in the DLD-1 IFT88-AID cell line, described in Fig 1.In order to investigate the effect of CW069-induced HSET inhibition on mitotic spindle morphology, as previously described for HSET depletion by siRNA (Kwon et al., 2008), we first confirmed the mitotic index, centrosome numbers, and extent of mitotic multipolarity in exponentially growing cultures of untreated N1E-115 and normal human dermal ...Dec 9, 2021 · Learn how you can join our team to tackle problems like this one by joining our Talent Network! Aug 19, 2022 · HSET key field value. Redis HSET command is used to set the field in the hash stored at key to value. If the key does not exist, a new key holding a hash is created. If the field already exists in the hash, it is overwritten. Syntax: HSET KEY_NAME FIELD VALUE Return Value. Integer reply. 1 if the field is a new field in the hash and value was set. The HISET Exam helps adult learners achieve their college and career goals. Find a test center location near you, or take the test at home. The Future Starts Here. Use EXPIRE or EXPIREAT command. If you want to expire specific keys in the hash older then 1 month. This is not possible. Redis expire command is for all keys in the hash. If you set daily hash key, you can set a keys time to live. hset key-20140325 f1 1 expire key-20140325 100 hset key-20140325 f1 2. Share.When Redis is compiled as a 32-bit target, it uses a lot less memory per key, since pointers are small, but such an instance will be limited to 4 GB of maximum memory usage. To compile Redis as 32-bit binary use make 32bit . RDB and AOF files are compatible between 32-bit and 64-bit instances (and between little and big endian of course) so you ... The most impactful addition to Redis version 7.0 is Redis Functions - a new programmability option, improving on scripts by adding modularity, reusability, and better overall developer experience. Functions are, in contrast to scripts, persisted in the .rdb and .aof files as well as automatically replicated to all the replicas, which makes them ...Aug 19, 2022 · HSET key field value. Redis HSET command is used to set the field in the hash stored at key to value. If the key does not exist, a new key holding a hash is created. If the field already exists in the hash, it is overwritten. Syntax: HSET KEY_NAME FIELD VALUE Return Value. Integer reply. 1 if the field is a new field in the hash and value was set. Jun 13, 2023 · High School Equivalency Tests (HSET) are designed for adults who do not have their high school diploma. In California the minimum age required to take one of The most impactful addition to Redis version 7.0 is Redis Functions - a new programmability option, improving on scripts by adding modularity, reusability, and better overall developer experience. Functions are, in contrast to scripts, persisted in the .rdb and .aof files as well as automatically replicated to all the replicas, which makes them ... Aug 19, 2022 · HMSET key field1 value1 [field2 value2 ] Redis HMSET command is used to set the specified fields to their respective values in the hash stored at key. This command overwrites any existing fields in the hash. If the key does not exist, a new key holding a hash is created. Kinesin-14/HSET, a minus end-directed motor, plays a crucial role in centrosome clustering. Accordingly, HSET is deemed to be a promising chemotherapeutic target to selectively kill cancer cells. Recently, three HSET inhibitors (AZ82, CW069 and SR31527) have been reported, but their specificity and efficacy have not been evaluated rigorously.Php Redis: Redis hash usage example - OneLinerHub Is getting data back from Redis SETS faster or more performant than HSETS? I currently have a scenario where we are using REDIS to store string field-value pairs within a hashed set HSET. The original reasoning behind using hashed sets instead of just sets is ease of retrieving the records using HSCAN inside a GUI Search Bar as opposed to just ...Jun 4, 2020 · Abstract. Centrosome amplification is a hallmark of cancer, and centrosome clustering is essential for cancer cell survival. The mitotic kinesin HSET is an essential contributor to this process. Recent studies have highlighted novel functions for intraflagellar transport (IFT) proteins in regulating motors and mitotic processes. Aug 29, 2020 · suyog August 29, 2020, 11:35am 2. @harry. you can set expiry to any Redis data types keys. below is example for Hashes. redis> HSET myhash field1 "helloworld" (integer) 0 redis> EXPIRE myhash 60 (integer) 1 redis> TTL myhash (integer) 51 redis> HGET myhash field1 "helloworld" redis> TTL myhash (integer) 10 redis> TTL myhash (integer) -2 redis ... Apr 10, 2021 · HKEYS client/9999/products 1) id_547 2) whatever_key_you_want. $this->_redis_client->hkeys ('client/9999/products') Unlike KEYS, the complexity of HKEYS is O (N) where N is the size of the hash (NOT the size of the entire database). If the keys get very large you may want to use HSCAN. Dec 11, 2014 · KIFC1 (HSET), a member of the kinesin-14 family of motor proteins, plays an essential role in centrosomal bundling in cancer cells, but its function is not required for normal diploid cell division. To explore the potential of KIFC1 as a therapeutic target for human cancers, a series of potent KIFC1 … Long. hset ( K key, Map < K, V > map) Set multiple hash fields to multiple values. Boolean. hsetnx ( K key, K field, V value) Set the value of a hash field, only if the field does not exist. Long. hstrlen ( K key, K field) Get the string length of the field value in a hash.Here we show that HSET promotes tumor progression via mechanisms independent of centrosome clustering. We found that HSET is overexpressed in breast carcinomas wherein nuclear HSET accumulation correlated with histological grade and predicted poor progression-free and overall survival.In Aim 3, the value of a promising commercially available HSET inhibitor will be tested in xenograft models of AA and EA TNBC patient-derived cells. Thus, this study will test the hypothesis that nHSET is a novel therapeutically actionable biomarker with greater value for AA than EA TNBC patients that drives TNBC progression and chemoresistance ...Jun 4, 2020 · Abstract. Centrosome amplification is a hallmark of cancer, and centrosome clustering is essential for cancer cell survival. The mitotic kinesin HSET is an essential contributor to this process. Recent studies have highlighted novel functions for intraflagellar transport (IFT) proteins in regulating motors and mitotic processes. HSET will be REMOTE on Friday, June 9, 2023 - Head to Google Classroom. Book a Virtual Teacher Tuesday meeting. Preparing for the brightest future, High School for Energy and Technology is pioneering the field of education through our dedication and commitment to our students’ needs.Aug 19, 2022 · HMSET key field1 value1 [field2 value2 ] Redis HMSET command is used to set the specified fields to their respective values in the hash stored at key. This command overwrites any existing fields in the hash. If the key does not exist, a new key holding a hash is created. HSET will be REMOTE on Friday, June 9, 2023 - Head to Google Classroom. Book a Virtual Teacher Tuesday meeting. Preparing for the brightest future, High School for Energy and Technology is pioneering the field of education through our dedication and commitment to our students’ needs.When Redis is compiled as a 32-bit target, it uses a lot less memory per key, since pointers are small, but such an instance will be limited to 4 GB of maximum memory usage. To compile Redis as 32-bit binary use make 32bit . RDB and AOF files are compatible between 32-bit and 64-bit instances (and between little and big endian of course) so you ... An HSET is like so: HSET myhash field1 "Hello" is there a way to put an expiration/TTL on the "field1" key. It's trivial to put an expiration on myhash tmk, but I don't know how to put a TTL on k...Jun 18, 2023 · Description. Set objects are collections of values. A value in the set may only occur once; it is unique in the set's collection. You can iterate through the elements of a set in insertion order. The insertion order corresponds to the order in which each element was inserted into the set by the add () method successfully (that is, there wasn't ... Redis Hset 命令. Redis 哈希(Hash) Redis Hset 命令用于为哈希表中的字段赋值 。 如果哈希表不存在,一个新的哈希表被创建并进行 HSET 操作。 如果字段已经存在于哈希表中,旧值将被覆盖。 语法. redis Hset 命令基本语法如下: redis 127.0.0.1:6379> HSET KEY_NAME FIELD VALUE 可用版本 HSET Day started out as Health Sciences and Nursing Day, but it evolved when GCU decided to emphasize science, technology, engineering and math. Several health sciences, engineering and technology clubs set up information tables for HSET Day, including athletic training (pictured).Sep 7, 2023 · HSET will be REMOTE on Friday, June 9, 2023 - Head to Google Classroom. Book a Virtual Teacher Tuesday meeting. Preparing for the brightest future, High School for Energy and Technology is pioneering the field of education through our dedication and commitment to our students’ needs. Best Java code snippets using redis.clients.jedis. Jedis.hset (Showing top 20 results out of 846) redis.clients.jedis Jedis hset. While working with Redis, I am running into an issue that the documentation doesn't really help much with. I am attempting to store scores as a hash within a stored value (so like a hash within group:id:ranking), which I thought would be written using hset or hmset and read using hget. When you pass the HiSET, you receive what's known as a high school equivalency credential (HSE), which essentially stands in for a high school diploma. In order to receive an HSE credential, you have to pass five subject sections of the HiSET, called subtests. These five subtests test you on language arts reading, language arts writing, math ...Here we show that HSET promotes tumor progression via mechanisms independent of centrosome clustering. We found that HSET is overexpressed in breast carcinomas wherein nuclear HSET accumulation correlated with histological grade and predicted poor progression-free and overall survival.May 21, 2021 · 0. short answer: it's not (but this is not the answer you're looking for). long answer: node-redis package will use the redis engine of the redis server instance being connected to. e.g. the client will not complain about HMSET deprecation when connected to redis server >=2.0,<4.0. Aug 19, 2022 · 127.0.0.1:6379> HSET user email [email protected] (integer) 1 127.0.0.1:6379> HSET user lang English (integer) 1 127.0.0.1:6379> HSET user gender Male ... KIFC1 (HSET), a member of the kinesin-14 family of motor proteins, plays an essential role in centrosomal bundling in cancer cells, but its function is not required for normal diploid cell division. To explore the potential of KIFC1 as a therapeutic target for human cancers, a series of potent KIFC1 …To extend that momentum, we’re now introducing the public preview of RediSearch 2.0, designed to improve the developer experience and be the most scalable version of Redisearch. RediSearch 2.0 supports Redis’ Active-Active geo-distribution technology, is scalable without downtime, and includes Redis on Flash support (currently in private ...2 Answers. Sorted by: 1. what you are doing is calling hset multiple times with a single key/value. which is bad because of the round trip latency. doing it to 10k key/value will be 10k round trips. you can use hset with multiple key/value so it will be a single trip to redis. eg. hset field1 value1 field2 value2 field3 value3.This suggests that only a subset of the IFT machinery, including IFT52 and IFT88, interacts with HSET to promote centrosome clustering. Figure 3. IFT 88/70/52/46 complex directly interacts with HSET, and depletion of IFT88 reduces HSET turnover on mitotic spindle microtubules. Schematic representing the core of IFT‐B subcomplex.HMSET key field1 value1 [field2 value2 ] Redis HMSET command is used to set the specified fields to their respective values in the hash stored at key. This command overwrites any existing fields in the hash. If the key does not exist, a new key holding a hash is created.For random integration of GFP-HSET and GFP-HSET N593K, 10 μg of linearized plasmid was electroporated into HSET KO cells using a gene pulser (Bio-Rad Laboratories) at 250 V and 950 μF.An In Silico Model for HSET Binding Informs Compound Design and Synthesis of the Allosteric HSET Inhibitor CW069. Amino acid sequence alignments for the motor domains of HSET (Protein Data Bank [PDB] 2REP) and the closely related kinesin, KSP (PDB 2FKY and 3ZCW), revealed an 80% sequence similarity between the proteins in the motor domains (HSET residues 310–661).

Redis HSET command is used to set field in the hash stored at the key to value. If the key does not exist, a new key holding a hash is created. If the field already exists in the hash, it is overwritten. Return Value. Integer reply . Things you can

chancepercent27s hset

Sep 7, 2023 · HSET will be REMOTE on Friday, June 9, 2023 - Head to Google Classroom. Book a Virtual Teacher Tuesday meeting. Preparing for the brightest future, High School for Energy and Technology is pioneering the field of education through our dedication and commitment to our students’ needs. Learn how you can join our team to tackle problems like this one by joining our Talent Network!While working with Redis, I am running into an issue that the documentation doesn't really help much with. I am attempting to store scores as a hash within a stored value (so like a hash within group:id:ranking), which I thought would be written using hset or hmset and read using hget. You can see some examples that use SORT in listing 3.12. The first few lines of the listing show the addition of some initial data, and basic sorting (by numeric value and by string order). The remaining parts show how we can store data to be sorted by and/or fetched inside HASH es using a special syntax. Start by adding some items to a LIST. Put on monitoring. status variable If Threads_connected reaches 70% of the max_connections your monitoring should send an alert and you must connect to the database and debug which user consumes the most connections. select count (*),user from information_schema.processlist group by user order by count (*) desc;Mar 7, 2013 · 5. The only difference between the commands HSET and HMSET is the return value of the commands. HSET return value (Integer reply): # if the field is a new field in the hash and value was set. (where # is the number of new fields created ) 0 if the field already exists in the hash and the value was updated. HMSET returns a simple string as a reply. May 21, 2021 · 0. short answer: it's not (but this is not the answer you're looking for). long answer: node-redis package will use the redis engine of the redis server instance being connected to. e.g. the client will not complain about HMSET deprecation when connected to redis server >=2.0,<4.0. Feb 4, 2021 · The documentation for Redis HSET states: 'As of Redis 4.0.0, HSET is variadic and allows for multiple field/value pairs.' Your solution is not the same as doing HMSET. Because that would only save a single string. I want to store the whole object in the database. To extend that momentum, we’re now introducing the public preview of RediSearch 2.0, designed to improve the developer experience and be the most scalable version of Redisearch. RediSearch 2.0 supports Redis’ Active-Active geo-distribution technology, is scalable without downtime, and includes Redis on Flash support (currently in private ...However, we are aware of the caveat that this mitotic role of HSET does not provide an alibi for the observed faster progression through the G2-phase upon HSET overexpression; (iii) HSET OE in HeLa cells leads to faster cell-cycle kinetics and enhanced overall proliferation (Fig. 5A, B, C), and (iv) HSET OE leads to the upregulation of the ...redis.hmset ('myKey', info) If you use Redis.hset () the following you will not get warning. redis.hset ('myKey', key=None, value=None, mapping=info) With this usage, we will skip the single key & value adding step and redis.hset () will set all of the key and value mappings in info to myKey. Share.When you pass the HiSET, you receive what's known as a high school equivalency credential (HSE), which essentially stands in for a high school diploma. In order to receive an HSE credential, you have to pass five subject sections of the HiSET, called subtests. These five subtests test you on language arts reading, language arts writing, math ... For random integration of GFP-HSET and GFP-HSET N593K, 10 μg of linearized plasmid was electroporated into HSET KO cells using a gene pulser (Bio-Rad Laboratories) at 250 V and 950 μF.Mar 1, 2021 · In Aim 3, the value of a promising commercially available HSET inhibitor will be tested in xenograft models of AA and EA TNBC patient-derived cells. Thus, this study will test the hypothesis that nHSET is a novel therapeutically actionable biomarker with greater value for AA than EA TNBC patients that drives TNBC progression and chemoresistance ... .

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